Chondral Defects involving the Articular cartilage of the knee joint present a challenge both in the Diagnosis & Management. The defects can be seen in the young patients following sports injuries or following a fall, in addition to the degenerative changes seen in the older patients. A lack of timely diagnosis & management, with improper healing leads to the development of Osteoarthritis.
There have been many surgical advancements in the field over the past few decades to repair the damaged cartilage & regenerate a healthy hyaline cartilage.
There has been an extensive Research in the field of Stem Cell Therapy over the past decade associated with the use of Chondroprogenitors & the Mesenchymal stem cells (MSCs) based therapies , used alone or in association with the surgical procedures to regenerate a healthy hyaline cartilage.
The recent trends in the field, along with the results of the ongoing clinical trials associated with the role of Stem Cell therapy & the Chondroprogenitors used alone & in combination with other techniques will be discussed.