The term "stem cells" refers to a variety of cells that have self-renewal and differentiation capabilities, many of which could be used therapeutically. As more stem cell-based medicines reach clinical trials, the necessity for strong methodologies and consistent procedures capable of reliably delivering the required volumes of cells while verifying the product's safety and usefulness becomes obvious. Over the last 50–60 years, the stem cell field has advanced dramatically. The development of cell-engineering techniques has ushered in a new era of stem cell-based therapeutics, considerably extending their therapeutic potential. These next-generation stem cells are being employed as 'Trojan horses' to increase medicine and oncolytic virus delivery to stubborn tumours, and they're also being modified with angiogenic, neurotrophic, and anti-inflammatory chemicals to speed tissue healing.